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Abstract This paper asserts that critiques of political science for neglecting Indigenous politics highlight a critical gap that risks overlooking significant conceptual and practical innovations. It emphasizes how Indigenous autonomy claims challenge traditional notions of sovereignty. Scholars of Indigenous politics in Latin America, publishing in area studies journals, provide essential insights into these autonomy claims and contribute valuable perspectives to the discipline. We identify rigorous scholarly work in English language, peer-reviewed journals exploring Indigenous autonomy, conceptualizing it as a multifaceted notion that encompasses political visions, practices, and social movement agendas. Through a comprehensive meta-analysis of literature in Latin American area studies, we argue that this field offers four fundamental insights. First, Indigenous peoples deploy diverse strategies to assert their rights, positioning themselves as active citizens and political agents rather than passive groups. Second, the emergence of multicultural institutions that integrate individual and collective rights is fundamentally reshaping politics and citizenship, leading to innovative governance structures. Third, accumulation by dispossession remains a crucial driver of wealth creation, severely undermining Indigenous autonomy and degrading their environments. Finally, a renewed emphasis on Indigenous territorial autonomy decisively challenges conventional views of state sovereignty, as Indigenous peoples assert territorial and nonterritorial rights. 

Abstract Background Hi-C experiments couple DNA-DNA proximity with next-generation sequencing to yield an unbiased description of genome-wide interactions. Previous methods describing Hi-C experiments have focused on the industry-standard Illumina sequencing. With new next-generation sequencing platforms such as BGISEQ-500 becoming more widely available, protocol adaptations to fit platform-specific requirements are useful to give increased choice to researchers who routinely generate sequencing data. Results We describe an in situ Hi-C protocol adapted to be compatible with the BGISEQ-500 high-throughput sequencing platform. Using zebra finch (Taeniopygia guttata) as a biological sample, we demonstrate how Hi-C libraries can be constructed to generate informative data using the BGISEQ-500 platform, following circularization and DNA nanoball generation. Our protocol is a modification of an Illumina-compatible method, based around blunt-end ligations in library construction, using un-barcoded, distally overhanging double-stranded adapters, followed by amplification using indexed primers. The resulting libraries are ready for circularization and subsequent sequencing on the BGISEQ series of platforms and yield data similar to what can be expected using Illumina-compatible approaches. Conclusions Our straightforward modification to an Illumina-compatible in situHi-C protocol enables data generation on the BGISEQ series of platforms, thus expanding the options available for researchers who wish to utilize the powerful Hi-C techniques in their research.